The Imperfect Cytokine Storm
نویسندگان
چکیده
منابع مشابه
Targeting the "cytokine storm" for therapeutic benefit.
Inflammation is the body's first line of defense against infection or injury, responding to challenges by activating innate and adaptive responses. Microbes have evolved a diverse range of strategies to avoid triggering inflammatory responses. However, some pathogens, such as the influenza virus and the Gram-negative bacterium Francisella tularensis, do trigger life-threatening "cytokine storms...
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The increasing insight into pathomechanisms of dysregulated host response in several inflammatory diseases led to the implementation of the term "cytokine storm" in the literature more than 20 years ago. Direct toxic effects as well as indirect immunomodulatory mechanisms during cytokine storm have been described and were the basis for the rationale to use several substances and devices in life...
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ژورنال
عنوان ژورنال: JACC: Case Reports
سال: 2020
ISSN: 2666-0849
DOI: 10.1016/j.jaccas.2020.04.001